ENHANCED THERAPEUTIC EFFICACY OF DOXORUBICIN AGAINST MULTIDRUG-RESISTANT BREAST CANCER WITH REDUCED CARDIOTOXICITY

Enhanced therapeutic efficacy of doxorubicin against multidrug-resistant breast cancer with reduced cardiotoxicity

AbstractDoxorubicin (DOX), a commonly used anti-cancer drug, is limited by its cardiotoxicity and multidrug resistance (MDR) of tumor cells.Epigallocatechin gallate (EGCG), a natural antioxidant component, can effectively reduce the cardiotoxicity of DOX.Meanwhile, EGCG can inhibit the expression of P-glycoprotein (P-gp) and reverse the MDR of tumo

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Detecting and Removing Text in the Wild

Scene text removal is a challenging task that aims to erase wild text regions T-Shirts that include text strokes and their ambiguous boundaries, such as embossing, shade, or flare.The challenging issues raised in the wild are not completely addressed by the existing methods.To address these issues, we propose a new loss function for blending two ta

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